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Hydroxy-PEG4-t-butyl ester

This product is for research use only, not for human use. We do not sell to patients.

Hydroxy-PEG4-t-butyl ester
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
2g$400Check With Us
5g$700Check With Us
10g$1050Check With Us

Cat #: V22333 CAS #: 518044-32-1 Purity ≥ 98%

Description: Hydroxy-PEG4-t-butyl ester is a PEG analogue containing a hydroxyl group with a t-butyl ester.

References: Qingqi Chen,et al. The use of isocyanate linkers to make hydrolyzable active agent biopolymer conjugates. Patent WO2004008101A2.

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Product Promise

Promise
Molecular Weight (MW)322.39
Molecular FormulaC15H30O7
CAS No.518044-32-1
SMILES CodeO=C(OC(C)(C)C)CCOCCOCCOCCOCCO
SynonymsHydroxy-PEG4-t-butyl ester
ProtocolIn VitroADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.1018 mL15.5092 mL31.0183 mL62.0367 mL
5mM0.6204 mL3.1018 mL6.2037 mL12.4073 mL
10mM0.3102 mL1.5509 mL3.1018 mL6.2037 mL
20mM0.1551 mL0.7755 mL1.5509 mL3.1018 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.