Hydrocortisone (Cortisol)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 10g | $150 | Check With Us |
| 100g | $750 | Check With Us |
| 200g | $1075 | Check With Us |
: Cat #: V1697 CAS #: 50-23-7 Purity ≥ 98%
Description: Hydrocortisone (Cortisol; H-Cort) is a steroid hormone and/or endogenous glucocorticoid produced by the adrenal gland for the treatment of adrenocortical insufficiency. .
Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products
Product Promise
- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 362.46 |
|---|---|
| Molecular Formula | C21H30O5 |
| CAS No. | 50-23-7 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 73 mg/mL (201.4 mM)r |
| Water:<1 mg/mLr | |
| Ethanol:<23 mg/mL (63.5 mM) | |
| Synonyms | Hydrocortisone; Cortisol; H-Cort |
| Protocol | In Vitro | Hydrocortisone (50 nM) shows dose-dependent downregulation of GR transcripts in hCMEC/D3 cells. Supplementation with Hydrocortisone in serum-reduced cell differentiation medium resulted in a significant increase in TER in the hCMEC/D3 monolayer |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.7589 mL | 13.7946 mL | 27.5893 mL | 55.1785 mL |
| 5mM | 0.5518 mL | 2.7589 mL | 5.5179 mL | 11.0357 mL |
| 10mM | 0.2759 mL | 1.3795 mL | 2.7589 mL | 5.5179 mL |
| 20mM | 0.1379 mL | 0.6897 mL | 1.3795 mL | 2.7589 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.