Hydrochloroquine sulfate (Hydroxychloroquine)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 5g | $345 | Check With Us |
| 10g | $445 | Check With Us |
| 20g | $665 | Check With Us |
: Cat #: V20371 CAS #: 747-36-4 Purity ≥ 98%
Description: Hydroxychloroquine sulfate (Hydrochloroquine) has been reported to be highly effective in fighting against SARS-CoV-2 (COVID-19, CoronaVirus) infections, the COVID-19 pandemic.
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| Molecular Weight (MW) | 433.948 |
|---|---|
| Molecular Formula | C18H28ClN3O5S |
| CAS No. | 747-36-4 |
| Synonyms | Ercoquin; Plaquinol; Toremonil; Oxychlorochin; Oxychloroquine; Plaquenil |
| Protocol | In Vitro | Hydroxychloroquine sulfate or chloroquine also has no measurable effect on intracellular pH, although these concentrations can inhibit DNA or RNA ligand-induced TLR9 or 7 signaling |
|---|---|---|
| In Vivo | Hydroxychloroquine sulfate is used to treat lupus, and hydroxychloroquine sulfate and its analogue chloroquine both inhibit TLR7 and 9 signaling |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.3044 mL | 11.5221 mL | 23.0442 mL | 46.0885 mL |
| 5mM | 0.4609 mL | 2.3044 mL | 4.6088 mL | 9.2177 mL |
| 10mM | 0.2304 mL | 1.1522 mL | 2.3044 mL | 4.6088 mL |
| 20mM | 0.1152 mL | 0.5761 mL | 1.1522 mL | 2.3044 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.