(-)-Huperzine A (HupA)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $700 | Check With Us |
| 1g | $1150 | Check With Us |
| 5g | $3450 | Check With Us |
: Cat #: V1082 CAS #: 102518-79-6 Purity ≥ 98%
Description: (-)-Huperzine A (Hup A; Selagine; (-)-Selagine) is a naturally occurring, highly specific and reversible inhibitor of acetylcholinesterase (AChE) with neuroprotective activity.
Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products
Product Promise
- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 242.32 |
|---|---|
| Molecular Formula | C15H18N2O |
| CAS No. | 102518-79-6 |
| Storage | -20℃ for 3 years in powder formrr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO:<1 mg/mLrr |
| Water: <1 mg/mLrr | |
| Ethanol:<1 mg/mL | |
| Solubility In Vivo | 30% propylene glycol, 5% Tween 80, 65% D5W: 30 mg/mL |
| Synonyms | Hup A; Huperzine A; Selagine; (-)-huperzine A; (-)-Selagine. |
| Protocol | In Vivo | (-)-Huperzine A (0.1-0.2 mg/kg； intraperitoneal injection; daily； for 12 days) alleviates cognitive dysfunction and neuronal degeneration caused by ICV infusion β-amyloid-(1-40) in rats |
|---|---|---|
| Animal model | Male Sprague-Dawley rats (220-280 g) | |
| Dosages | 0.1 mg/kg, 0.2 mg/kg | |
| Administration | Intraperitoneal injection, daily, for 12 days |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 4.1268 mL | 20.6339 mL | 41.2677 mL | 82.5355 mL |
| 5mM | 0.8254 mL | 4.1268 mL | 8.2535 mL | 16.5071 mL |
| 10mM | 0.4127 mL | 2.0634 mL | 4.1268 mL | 8.2535 mL |
| 20mM | 0.2063 mL | 1.0317 mL | 2.0634 mL | 4.1268 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.