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Guanfacine HCl

This product is for research use only, not for human use. We do not sell to patients.

Guanfacine HCl
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
25mg$120To Be Confirmed
50mg$190To Be Confirmed
100mg$285To Be Confirmed
250mg$480To Be Confirmed
500mg$690To Be Confirmed
1g$980To Be Confirmed
email: [email protected]        [email protected]

Cat #: V5029 CAS #: 249-443-3 Purity ≥ 98%

Description: Guanfacine HCl, the hydrochloride salt of Guanfacine, is a potent, selective and centrally acting alpha-2 adrenergic agonist with antihypertensive activity and with Kd of 31 nM. It displays 60-fold selectivity over α2B-adrenoceptors. Alpha-2 receptor stimulation by guanfacine hydrochloride results in a decreased sympathetic outflow from the vasomotor center to the heart, kidneys, and peripheral vasculature. This leads to a decrease in heart rate and peripheral vascular resistance.

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CAS No.249-443-3
Storage-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
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Concentration
 
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Volume
 
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
×
 
Volume(start)
V1
 
=
 
Concentration(final)
C2
 
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.