GSK484

This product is for research use only, not for human use. We do not sell to patients.

GSK484
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$1250Check With Us
250mg$2050Check With Us
500mg$3075Check With Us

Cat #: V3606 CAS #: 1652591-81-5 Purity ≥ 98%

Description: GSK484 is a novel and potent inhibitor of peptidylarginine deiminase 4 (PAD4).

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Product Promise

Promise
Molecular Weight (MW)510.035
Molecular FormulaC27H32ClN5O3
CAS No.1652591-81-5
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
SMILES CodeO=C(N1C[C@H](N)[C@H](O)CC1)C2=CC(OC)=C3N(C)C(C(N4CC5CC5)=CC6=C4C=CC=C6)=NC3=C2.[H]Cl
SynonymsGSK484; GSK-484; GSK 484
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.9606 mL9.8032 mL19.6065 mL39.2130 mL
5mM0.3921 mL1.9606 mL3.9213 mL7.8426 mL
10mM0.1961 mL0.9803 mL1.9606 mL3.9213 mL
20mM0.0980 mL0.4902 mL0.9803 mL1.9606 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.