GSK2879552

This product is for research use only, not for human use. We do not sell to patients.

GSK2879552
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1150Check With Us
500mg$1780Check With Us
1g$2670Check With Us

Cat #: V3597 CAS #: 1401966-69-5 Purity ≥ 98%

Description: GSK2879552 (GSK-2879552) is a novel, potent and orally bioavailable, irreversible inhibitor of lysine specific demethylase 1 (LSD1) with potential anticancer activity.

References: Huang M, et al. Targeting KDM1A attenuates Wnt/β-catenin signaling pathway to eliminate sorafenib-resistant stem-like cells in hepatocellular carcinoma. Cancer Lett. 2017 Apr 2;398:12-21

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Product Promise

Promise
Molecular Weight (MW)364.48
Molecular FormulaC23H28N2O2
CAS No.1401966-69-5
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
SMILES CodeO=C(O)C1=CC=C(CN2CCC(CN[C@H]3[C@H](C4=CC=CC=C4)C3)CC2)C=C1
SynonymsGSK2879552; GSK-2879552; GSK 2879552.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.7436 mL13.7182 mL27.4363 mL54.8727 mL
5mM0.5487 mL2.7436 mL5.4873 mL10.9745 mL
10mM0.2744 mL1.3718 mL2.7436 mL5.4873 mL
20mM0.1372 mL0.6859 mL1.3718 mL2.7436 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.