GSK-626616

This product is for research use only, not for human use. We do not sell to patients.

GSK-626616
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5mg$1103-6 Days
10mg$1803-6 Days
25mg$2903-6 Days
50mg$4403-6 Days
100mg$6603-6 Days
email: sales@invivochem.com        sales@invivochem.cn

Cat #: V21894 CAS #: 1025821-33-3 Purity ≥ 99%

Description: GSK 626616 is a novel, potent, and orally bioavailable YAK3/DYRK3 kinase inhibitor with IC50 of 0.7 nM for DYRK3. Possibly used to treat anemia brought on by chemotherapy, it is a chemoprotective agent.

Top Publications Citing Invivochem Products
Product Catalog 2022
Bulletin Board
Guide to Product Handling
Publications Citing InvivoChem Products
Product Promise
Promise
Molecular Weight (MW)401.269199848175
Molecular FormulaC18H10Cl2N4OS
CAS No.1025821-33-3
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

SynonymsGSK626616; GSK 626616; GSK-626616
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.4921 mL12.4605 mL24.9209 mL49.8419 mL
5mM0.4984 mL2.4921 mL4.9842 mL9.9684 mL
10mM0.2492 mL1.2460 mL2.4921 mL4.9842 mL
20mM0.1246 mL0.6230 mL1.2460 mL2.4921 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
=
Concentration
 
×
Volume
 
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
×
 
Volume(start)
V1
 
=
 
Concentration(final)
C2
 
×
 
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.