GC376 sodium
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $550 | In Stock |
| 1g | $900 | In Stock |
| 5g | $1520 | In Stock |
: Cat #: V21529 CAS #: 1416992-39-6 Purity ≥ 98%
Description: GC376 sodium (GC-376), the sodium salt of GC376, is a potent inhibitor of 3C-like proteases (3CLpro) with IC50 values ranging from 0.49 to 4.35 μM.
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| Molecular Weight (MW) | C21H30N3NaO8S |
|---|---|
| Molecular Formula | 507.53 |
| CAS No. | 1416992-39-6 |
| SMILES Code | O=S(C(O)[C@@H](NC([C@@H](NC(OCC1=CC=CC=C1)=O)CC(C)C)=O)CC2C(NCC2)=O)([O-])=O.[Na+] |
| Synonyms | GC376; GC-376; GC 376; GC376 sodium. |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
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Volume(start)
=
Concentration(final)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
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C1
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Volume(start)
V1
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Concentration(final)
C2
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Volume(final)
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.