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Garenoxacin mesylate hydrate

This product is for research use only, not for human use. We do not sell to patients.

Garenoxacin mesylate hydrate
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$480Check With Us
250mg$900Check With Us
500mg$1350Check With Us

Cat #: V21516 CAS #: 223652-90-2 Purity ≥ 98%

Description: Garenoxacin mesylate hydrate (BMS-284756; tradename: Geninax), the hydrated and mesylate salt of Garenoxacin, is an orally bioavailable quinolone-based antibiotic for the treatment of Gram-positive and Gram-negative bacterial infections.

References: Waites KB, et al. In vitro susceptibilities to and bactericidal activities of garenoxacin (BMS-284756) and other antimicrobial agents against human mycoplasmas and ureaplasmas. Antimicrob Agents Chemother. 2003 Jan;47(1):161-5.

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Product Promise

Promise
Molecular Weight (MW)540.53
Molecular FormulaC24H26F2N2O8S
CAS No.223652-90-2
ProtocolIn VitroGarenoxacin (BMS284756) (0-8 days) inhibits mycoplasmas and ureaplasmas with MIC90s ≤0.25 μg/mL against tested strains
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.8500 mL9.2502 mL18.5004 mL37.0007 mL
5mM0.3700 mL1.8500 mL3.7001 mL7.4001 mL
10mM0.1850 mL0.9250 mL1.8500 mL3.7001 mL
20mM0.0925 mL0.4625 mL0.9250 mL1.8500 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.