Garcinone C

This product is for research use only, not for human use. We do not sell to patients.

Garcinone C
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5mg$90To Be Confirmed
email: [email protected]        [email protected]

Cat #: V29374 CAS #: 76996-27-5 Purity ≥ 99%

Description: Garcinone C is a xanthone analogue, a natural compound found in Garcinia oblongifolia. It is used as an anti~inflammatory, astringent and granulation-promoting active molecule and may be utilized in certain cancers. cell toxicity/cytotoxicity. Garcinone C stimulates the expression levels of ATR and 4E-BP1, while effectively inhibiting the expression levels of cyclin B1, cyclin D1, cyclin E2, cdc2, Stat3 and CDK7. Garcinone C significantly inhibits the cell viability of human nasopharyngeal carcinoma (NPC) cell lines CNE1, CNE2, HK1 and HONE1 in a time- and dose-dependent fashion.

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Molecular Weight (MW)414.4483
Molecular FormulaC23H26O7
CAS No.76996-27-5
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

Note: This product requires protection from light (avoid light exposure) during transportation and storage.

Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.4128 mL12.0642 mL24.1285 mL48.2569 mL
5mM0.4826 mL2.4128 mL4.8257 mL9.6514 mL
10mM0.2413 mL1.2064 mL2.4128 mL4.8257 mL
20mM0.1206 mL0.6032 mL1.2064 mL2.4128 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
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Volume(start)
V1
 
=
 
Concentration(final)
C2
 
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Volume(final)
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.