Gallopamil HCl (Methoxyverapamil)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
100mg | $750 | To Be Confirmed |
250mg | $1450 | To Be Confirmed |
500mg | $2175 | To Be Confirmed |
Cat #: V40106 CAS #: 16662-46-7 Purity ≥ 99%
Description: Gallopamil HCl (Methoxyverapamil HCl), a methoxy analog of Verapamil, is a a coronary vasodilator and a phenylalkylamine calcium antagonist.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
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Molecular Weight (MW) | 521.09 |
---|---|
Molecular Formula | C₂₈H₄₁ClN₂O₅ |
CAS No. | 16662-46-7 |
SMILES Code | c1(OC)c(OC)cc(cc1OC)[C@@](CCC[N@@](CCc1ccc(c(c1)OC)OC)C)(C(C)C)C#N.Cl |
Protocol | In Vivo | Gallopamil hydrochloride (Methoxyverapamil hydrochloride; i.v.; 0.2 mg/kg; for 5 min) markedly reduces ventricular tachycardia (VT) and totally prevents fibrillation (VF). Gallopamil significantly reduces systolic and diastolic blood pressure measured 5 min after injection without markedly influencing heart rate |
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Animal model | Male Wistar rats weighing 290-370 g | |
Dosages | 0.2 mg/kg |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 1.9191 mL | 9.5953 mL | 19.1905 mL | 38.3811 mL |
5mM | 0.3838 mL | 1.9191 mL | 3.8381 mL | 7.6762 mL |
10mM | 0.1919 mL | 0.9595 mL | 1.9191 mL | 3.8381 mL |
20mM | 0.0960 mL | 0.4798 mL | 0.9595 mL | 1.9191 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.