FTO-IN-1

This product is for research use only, not for human use. We do not sell to patients.

FTO-IN-1
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5mg$2303-6 Days
10mg$3203-6 Days
25mg$5303-6 Days
50mg$7703-6 Days
100mg$10103-6 Days
250mg$14203-6 Days
email: sales@invivochem.com        sales@invivochem.cn

Cat #: V2426 CAS #: 2243944-92-3 Purity ≥ 99%

Description: FTO-IN-1 is an inhibitor (blocker/antagonist) of fat and obesity-related enzymes (FTO) with IC50 of <1 μM. FTO-IN-1 may be utilized in cancer-related research. For more details, check and find compound 32 from the patent WO2018157843A1.

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Molecular Weight (MW)391.2512
Molecular FormulaC18H16Cl2N4O2
CAS No.2243944-92-3
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

SynonymsFTO-IN1FTO-IN-1FTO-IN 1
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.5559 mL12.7795 mL25.5590 mL51.1181 mL
5mM0.5112 mL2.5559 mL5.1118 mL10.2236 mL
10mM0.2556 mL1.2780 mL2.5559 mL5.1118 mL
20mM0.1278 mL0.6390 mL1.2780 mL2.5559 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
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Volume
 
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
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Volume(start)
V1
 
=
 
Concentration(final)
C2
 
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.