Fremanezumab

This product is for research use only, not for human use. We do not sell to patients.

Fremanezumab
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
1mg$2703-6 Days

Cat #: V49766 CAS #: 1655501-53-3 Purity ≥ 99%

Description: Fremanezumab (TEV-48125) is a humanized IgG2a monoclonal antibody (mAb) that selectively and potently binds to calcitonin gene-related peptide (CGRP). CGRP is a 37-amino acid (AA) neuropeptide involved in central and peripheral pathophysiological events in migraine. Fremanezumab has potential usefulness in chronic migraine research.

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CAS No.1655501-53-3
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.