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| Size | Price | Stock |
|---|---|---|
| 10mg | $110 | 3-6 Days |
| 25mg | $170 | 3-6 Days |
| 50mg | $270 | 3-6 Days |
| 100mg | $400 | 3-6 Days |
: Cat #: V21365 CAS #: 28808-62-0 Purity ≥ 99%
Description: Fraxinellone is a naturally occurring anti-inflammatory agent isolated from the root bark of the Rutaceae plant, Dictamnus dasycarpus. Fraxinellone acts a PD-L1 inhibitor and inhibitor of HIF-1α protein synthesis without affecting HIF-1α protein degradation. Fraxinellone was able to inhibit LPS-induced nitric oxide (NO) and prostaglandin E(2) (PGE(2)) production, and to reduce the LPS-induced expressions of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) at the mRNA and protein levels in a dose-dependent manner.
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| Molecular Weight (MW) | 232.2750 |
|---|---|
| Molecular Formula | C14H16O3 |
| CAS No. | 28808-62-0 |
| Storage | Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 4.3052 mL | 21.5262 mL | 43.0524 mL | 86.1048 mL |
| 5mM | 0.8610 mL | 4.3052 mL | 8.6105 mL | 17.2210 mL |
| 10mM | 0.4305 mL | 2.1526 mL | 4.3052 mL | 8.6105 mL |
| 20mM | 0.2153 mL | 1.0763 mL | 2.1526 mL | 4.3052 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.