Fmoc-Val-Cit-PAB-MMAE
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $4950 | To Be Confirmed |
| 200mg | $7425 | To Be Confirmed |
| 500mg | $12530 | To Be Confirmed |
: Cat #: V33147 CAS #: 1350456-56-2 Purity ≥ 99%
Description: Fmoc-Val-Cit-PAB-MMAE is a novel drug-linker conjugate used for ADC.
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- Physicochemical and Storage Information
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| Molecular Weight (MW) | 1345.67 |
|---|---|
| Molecular Formula | C73H104N10O14 |
| CAS No. | 1350456-56-2 |
| SMILES Code | O=C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(COC(N(C)[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N(C)[C@]([C@@H](C)CC)([H])[C@H](OC)CC(N(CCC2)[C@]2([H])[C@H](OC)[C@@H](C)C(N[C@H](C)[C@H](C3=CC=CC=C3)O)=O)=O)=O)=O)=O)C=C1)=O)=O)OCC4C5=CC=CC=C5C6=CC=CC=C46 |
| Synonyms | Fmoc-Val-Cit-PAB-MMAE |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 0.7431 mL | 3.7156 mL | 7.4312 mL | 14.8625 mL |
| 5mM | 0.1486 mL | 0.7431 mL | 1.4862 mL | 2.9725 mL |
| 10mM | 0.0743 mL | 0.3716 mL | 0.7431 mL | 1.4862 mL |
| 20mM | 0.0372 mL | 0.1858 mL | 0.3716 mL | 0.7431 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.