Fluocinolone Acetonide

This product is for research use only, not for human use. We do not sell to patients.

Fluocinolone Acetonide
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5g$320Check With Us
10g$550Check With Us
20g$825Check With Us

Cat #: V1717 CAS #: 67-73-2 Purity ≥ 98%

Description: Fluocinolone Acetonide (Flucort-N; Flucinar, Fluonid, Synandone, Jellin, Sinalar) is a topical and synthetic glucocorticoid with with anti-inflammatory and immunomodulating properties.

References: Nehme, A., et al., Glucocorticoids with different chemical structures but similar glucocorticoid receptor potency regulate subsets of common and unique genes in human trabecular meshwork cells. BMC Med Genomics, 2009. 2: p. 58.

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Product Promise

Promise
Molecular Weight (MW)452.49
Molecular FormulaC24H30F2O6
CAS No.67-73-2
Storage-20℃ for 3 years in powder formrr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 90 mg/mL (198.89 mM)rr
Water: <1 mg/mLrr
Ethanol: 12 mg/mL (26.51 mM)
SynonymsFlucort-N; Flucinar, Fluonid, Fluocinolone Acetonide, Synandone, Jellin, Sinalar
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.2100 mL11.0500 mL22.0999 mL44.1999 mL
5mM0.4420 mL2.2100 mL4.4200 mL8.8400 mL
10mM0.2210 mL1.1050 mL2.2100 mL4.4200 mL
20mM0.1105 mL0.5525 mL1.1050 mL2.2100 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.