Finasteride (MK-906)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 2g | $520 | Check With Us |
| 5g | $820 | Check With Us |
| 10g | $1230 | Check With Us |
: Cat #: V1809 CAS #: 98319-26-7 Purity ≥ 98%
Description: Finasteride (also known as MK-906) is a potent, reversible, and orally bioactive inhibitor of the rat type II 5 alpha-reductase with Ki of 10.2 nM, used in the treatment of benign prostatic hyperplasia (BPH) and male pattern baldness (MPB).
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 372.54 |
|---|---|
| Molecular Formula | C23H36N2O2 |
| CAS No. | 98319-26-7 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 75 mg/mL (201.3 mM)r |
| Water:<1 mg/mLr | |
| Ethanol: 75 mg/mL (201.3 mM) | |
| Synonyms | MK-906; MK906; Proscar, Eucoprost, Propecia, MK 906 |
| Protocol | In Vivo | Finasteride (0.1-0.5 mg/kg; p.o. once daily for 16 weeks) reduces prostatic size in dogs with BPH without adversely affecting semen quality or serum testosterone concentration |
|---|---|---|
| Animal model | Male dogs with spontaneous BPH (2.7-11 years old; 10.3-49 kg) | |
| Dosages | 0.1-0.5 mg/kg | |
| Administration | P.o. once daily for 16 weeks |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.6843 mL | 13.4214 mL | 26.8428 mL | 53.6855 mL |
| 5mM | 0.5369 mL | 2.6843 mL | 5.3686 mL | 10.7371 mL |
| 10mM | 0.2684 mL | 1.3421 mL | 2.6843 mL | 5.3686 mL |
| 20mM | 0.1342 mL | 0.6711 mL | 1.3421 mL | 2.6843 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.