Finafloxacin (Xtoro)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
100mg	$1850	To Be Confirmed
200mg	$2275	To Be Confirmed
500mg	$4680	To Be Confirmed

: [email protected] [email protected]

Cat #: V16800 CAS #: 209342-40-5 Purity ≥ 98%

Description: Finafloxacin (trade name Xtoro) is an FDA approved fluoroquinolone antibiotic to treat acute otitis externa (so called swimmer's ear) caused by the bacteria Pseudomonas aeruginosa and Staphylococcus aureus.

References: McKeage K. Finafloxacin: first global approval. Drugs. 2015 Apr;75(6):687-93.

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Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	398.39
Molecular Formula	C20H19FN4O4
CAS No.	209342-40-5
SMILES Code	O=C(C1=CN(C2CC2)C3=C(C=C(F)C(N4C[C@]5([H])OCCN[C@@]5([H])C4)=C3C#N)C1=O)O
Synonyms	Finafloxacin, brand name Xtoro

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.5101 mL	12.5505 mL	25.1010 mL	50.2021 mL
5mM	0.5020 mL	2.5101 mL	5.0202 mL	10.0404 mL
10mM	0.2510 mL	1.2551 mL	2.5101 mL	5.0202 mL
20mM	0.1255 mL	0.6275 mL	1.2551 mL	2.5101 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.