This product is for research use only, not for human use. We do not sell to patients.
| Size | Price | Stock |
|---|---|---|
| 5mg | $55 | 3-6 Days |
| 10mg | $78 | 3-6 Days |
| 25mg | $115 | 3-6 Days |
| 50mg | $170 | 3-6 Days |
| 100mg | $255 | 3-6 Days |
| 250mg | $445 | 3-6 Days |
| 500mg | $650 | 3-6 Days |
: Cat #: V4802 CAS #: 151801-76-2 Purity ≥ 98%
Description: EXP-3174 (also known as losartan aarboxylic acid), a physiologically active metabolite of losartan produced by cytochrome P450 isoforms in the liver, is a non-peptide, potent angiotensin II (AII) receptor, type 1 (AT1) antagonist, which inhibits the AII induced cellular responses. Like the parent compound losartan, EXP-3174 is a potent AT1 antagonist with Kis of 0.57 and 0.67 nM for rat and human forms, respectively. It produces a depressor response and vasodilatation. When administered intravenously, losartan carboxylic acid is more potent and has a longer duration of action than losartan. However, the metabolite has very low oral bioavailability.
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| CAS No. | 151801-76-2 |
|---|---|
| Storage | -20℃ for 3 years in powder form |
| -80℃ for 2 years in solvent |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.