Etonogestrel

This product is for research use only, not for human use. We do not sell to patients.

Etonogestrel
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$520To Be Confirmed
250mg$950To Be Confirmed
500mg$1425To Be Confirmed

Cat #: V20831 CAS #: 54048-10-1 Purity ≥ 99%

Description: Etonogestrel (ORG3236; ORG-3236; Nexplanon; Implano; NuvaRing; Circlet) is an active metabolite of desogestrel and long-acting synthetic progestin derivative that has been used as a hormonal contraceptive drug in many devices.

References: Dionne D. Maddox, et al. Etonogestrel (Implanon), Another Treatment Option for Contraception. P T. 2008 Jun; 33(6): 337–347.

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Molecular Weight (MW)324.46
Molecular FormulaC22H28O2
CAS No.54048-10-1
SMILES CodeCC[C@]12CC(=C)[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=CC(=O)CC[C@H]34
SynonymsORG 3236; ORG-3236; 3-oxo desogestrel, 3-oxodesogestrel; ORG3236; Etonogestrel, Implanon, nexplanon, 3-keto-desogestrel, 3-ketodesogestrel,
ProtocolIn VitroEtonogestrel, a progestin, is a substrate of the CYP 3A4 oxidase system. Etonogestrel also increases the viscosity of cervical mucus, which hinders the passage of spermatozoa and alters the lining of the uterus to prevent implantation of a fertilized egg into the endometrium. Etonogestrel inhibits fertility by inhibiting the release of luteinizing hormone (LH), one of the reproductive hormones important in ovulation.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.0820 mL15.4102 mL30.8204 mL61.6409 mL
5mM0.6164 mL3.0820 mL6.1641 mL12.3282 mL
10mM0.3082 mL1.5410 mL3.0820 mL6.1641 mL
20mM0.1541 mL0.7705 mL1.5410 mL3.0820 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.