ETELCALCETIDE HCL

This product is for research use only, not for human use. We do not sell to patients.

ETELCALCETIDE HCL
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5mg$903-6 Days
10mg$1303-6 Days
25mg$2103-6 Days
50mg$3203-6 Days
100mg$4403-6 Days
250mg$6503-6 Days
email: [email protected]        [email protected]

Cat #: V3933 CAS #: 1334237-71-6 Purity ≥ 99%

Description: Etelcalcetide HCl (formerly known as ONO-5163; AMG-416, KAI-4169 and velcalcetide, Parsabiv), the hydrochloride salt of Etelcalcetide, is an agonist of calcium-sensing receptor that has been approved by FDA in 2017 as a calcimimetic drug for the treatment of secondary hyperparathyroidism in CKD (chronic kidney disease) patients undergoing hemodialysis.

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Molecular Weight (MW)1084.72
Molecular FormulaC38H74ClN21O10S2
CAS No.1334237-71-6
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

Note: Please store this product in a sealed and protected environment (e.g. under nitrogen), avoid exposure to moisture and light.

SynonymsVelcalcetide HCl; AMG-416 HCl; ONO5163; ONO-5163 HCl; AMG416; KAI 4169; KAI4169; AMG 416; KAI-4169; ONO 5163; Etelcalcetide; Velcalcetide; trade name Parsabiv; Telcalcetide; Ac-D-Cys-D-Ala-D-Arg-D-Arg-D-Arg-D-Ala-D-Arg-NH2 HCl
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM0.9219 mL4.6095 mL9.2190 mL18.4379 mL
5mM0.1844 mL0.9219 mL1.8438 mL3.6876 mL
10mM0.0922 mL0.4609 mL0.9219 mL1.8438 mL
20mM0.0461 mL0.2305 mL0.4609 mL0.9219 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.