Esomeprazole Magnesium; S-Omeprazole magnesium trihydrate;Omeprazole magnesium | Nexium"/>
Esomeprazole magnesium

This product is for research use only, not for human use. We do not sell to patients.

Esomeprazole magnesium
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
1g$650Check With Us
2g$950Check With Us
5g$1550Check With Us

Cat #: V33616 CAS #: 1198768-91-0 Purity ≥ 99%

Description: Esomeprazole magnesium, the magnesium salt of esomeprazole, is a potent proton pump inhibitor (PPI) with potential usefulness in the treatment of gastroesophageal reflux disease-GERD.

References: Wayne Goh, et al. Use of proton pump inhibitors as adjunct treatment for triple-negative breast cancers. An introductory study. J Pharm Pharm Sci. 2014;17(3):439-46.

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Molecular Weight (MW)369.72
Molecular FormulaC₁₇H₁₉MgN₃O₃S
CAS No.1198768-91-0
Synonyms <span id="xn_c_prodv_37_conT1_t">Esomeprazole Magnesium; </span>S-Omeprazole magnesium trihydrate;<span id="xn_c_prodv_37_conT1_t">Omeprazole magnesium; Nexium
ProtocolIn VitroEsomeprazole (25-100 µM; 20 hours; MDA-MB-468 cells) treatment suppresses growth of triple-negative breast cancer cell in vitro in a dose-dependent manner through increase in their intracellular acidification
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.7047 mL13.5237 mL27.0475 mL54.0950 mL
5mM0.5409 mL2.7047 mL5.4095 mL10.8190 mL
10mM0.2705 mL1.3524 mL2.7047 mL5.4095 mL
20mM0.1352 mL0.6762 mL1.3524 mL2.7047 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.