EPZ031686
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $2200 | To Be Confirmed |
| 200mg | $3300 | To Be Confirmed |
| 500mg | $5565 | To Be Confirmed |
: Cat #: V20667 CAS #: 1808011-22-4 Purity ≥ 98%
Description: EPZ-031686 (EPZ031686) is a potent, selective and orally bioavailable SMYD3 (Set and Mynd Domain containing 3) inhibitor with potential antitumor activity.
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- Physicochemical and Storage Information
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- Related Biological Data
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| Molecular Weight (MW) | 591.09 |
|---|---|
| Molecular Formula | C26H34ClF3N4O4S |
| CAS No. | 1808011-22-4 |
| SMILES Code | O=C(C1=CC2=C(NC(C2)=O)C=C1Cl)N[C@H]3C[C@@](N4S(=O)(CC5CCN(CCCC(F)(F)F)CC5)=O)([H])CC[C@@]4([H])C3 |
| Synonyms | EPZ-031686; EPZ031686; EPZ 031686 |
| Protocol | In Vivo | EPZ031686 (1-50 mg/mL; p.o. and i.v.; Male CD-1 mice) has good bioavailability following oral dosing in mice. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.6918 mL | 8.4589 mL | 16.9179 mL | 33.8358 mL |
| 5mM | 0.3384 mL | 1.6918 mL | 3.3836 mL | 6.7672 mL |
| 10mM | 0.1692 mL | 0.8459 mL | 1.6918 mL | 3.3836 mL |
| 20mM | 0.0846 mL | 0.4229 mL | 0.8459 mL | 1.6918 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.