EPRISTERIDE

This product is for research use only, not for human use. We do not sell to patients.

EPRISTERIDE
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$1680To Be Confirmed
250mg$2688To Be Confirmed
500mg$4032To Be Confirmed

Cat #: V3963 CAS #: 119169-78-7 Purity ≥ 98%

Description: Epristeride (ONO-9302; SKF105657; sold under the brand names Aipuliete and Chuanliu) is an orally available medication used for the treatment of enlarged prostate in China.

References: M A Levy, et al. Epristeride is a selective and specific uncompetitive inhibitor of human steroid 5 alpha-reductase isoform 2. J Steroid Biochem Mol Biol. 1994 Feb;48(2-3):197-206.

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Molecular Weight (MW)399.57
Molecular FormulaC₂₅H₃₇NO₃
CAS No.119169-78-7
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 10 mMr
Water: N/Ar
Ethanol: N/A
SMILES CodeC[C@@]12[C@](CC[C@@H]2C(NC(C)(C)C)=O)([H])[C@@]3([H])[C@]([C@@]4(C(C=C(C(O)=O)CC4)=CC3)C)([H])CC1
SynonymsONO-9302; SKF-105657; ONO9302; SKF105657; ONO 9302; SKF 105657; Brand name in China: Aipuliete and Chuanliu
ProtocolIn VitroEpristeride has inhibitory effects for SR isoenzymes types 2 (SR2) with Ki values of 0.7-2 nM.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.5027 mL12.5135 mL25.0269 mL50.0538 mL
5mM0.5005 mL2.5027 mL5.0054 mL10.0108 mL
10mM0.2503 mL1.2513 mL2.5027 mL5.0054 mL
20mM0.1251 mL0.6257 mL1.2513 mL2.5027 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.