Eprazinone diHCl
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 50g | $400 | Check With Us |
| 100g | $650 | Check With Us |
| 200g | $975 | Check With Us |
: Cat #: V38701 CAS #: 10402-53-6 Purity ≥ 99%
Description: Eprazinone diHCl, the dihydrochloride salt of Eprazinone, is a novel and potent neurokinin 1 receptor (NK1R) ligand with mucolytic, secretolytic, and bronchial antispasmodic activities.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
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| Molecular Weight (MW) | 453.44 |
|---|---|
| Molecular Formula | C24H34Cl2N2O2 |
| CAS No. | 10402-53-6 |
| Protocol | In Vitro | Eprazinone specifically displaces binding to the NK1R. Although Eprazinone displays a rather weak inhibition of [125I]BH-SP binding to NK1R, at a concentration of 25 μM, and an antagonistic effect of about 30%, NK1R blockade could contribute to its mucolytic activity |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.2054 mL | 11.0268 mL | 22.0536 mL | 44.1073 mL |
| 5mM | 0.4411 mL | 2.2054 mL | 4.4107 mL | 8.8215 mL |
| 10mM | 0.2205 mL | 1.1027 mL | 2.2054 mL | 4.4107 mL |
| 20mM | 0.1103 mL | 0.5513 mL | 1.1027 mL | 2.2054 mL |
The molarity calculator equation
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The dilution calculator equation
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This equation is commonly abbreviated as: C1 V1 = C2 V2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.