Epinastine HCl (WAL801)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
1g	$430	Check With Us
2g	$650	Check With Us
5g	$980	Check With Us

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Cat #: V1214 CAS #: 108929-04-0 Purity ≥ 98%

Description: Epinastine HCl (WAL801CL; Alesion; Elestat; Epinastine; Epinastin; WAL-801CL), the hydrochloride salt of epinastine, is a potent antagonist of histamine H1 receptors without sedative side effects.

References: C Kamei, et al. Antiallergic effect of epinastine (WAL 801 CL) on immediate hypersensitivity reactions: (I). Elucidation of the mechanism for histamine release inhibition. Immunopharmacol Immunotoxicol. 1992;14(1-2):191-205.

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Physicochemical and Storage Information
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Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	285.77
Molecular Formula	C16H15N3.HCl
CAS No.	108929-04-0
Storage	-20℃ for 3 years in powder formrr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 57 mg/mL (199.5 mM)rr
	Water: N/Arr
	Ethanol: 57 mg/mL (199.5 mM)
Solubility In Vivo	Chemical Name: 3-Amino-9,13b-dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepine Hydrochloride InChi Key: VKXSGUIOOQPGAF-UHFFFAOYSA-N InChi Code: InChI=1S/C16H15N3.ClH/c17-16-18-10-15-13-7-3-1-5-11(13)9-12-6-2-4-8-14(12)19(15)16;/h1-8,15H,9-10H2,(H2,17,18);1H SMILES Code: C1C2C3=CC=CC=C3CC4=CC=CC=C4N2C(=N1)N.Cl
Synonyms	WAL-801CL HCl; WAL801CL HCl; Alesion; Elestat; Epinastine HCl; Epinastin HCl; WAL 801CL HCl; WAL-801-CL HCl; Epinastine Hydrochloride;

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	3.4993 mL	17.4966 mL	34.9932 mL	69.9864 mL
5mM	0.6999 mL	3.4993 mL	6.9986 mL	13.9973 mL
10mM	0.3499 mL	1.7497 mL	3.4993 mL	6.9986 mL
20mM	0.1750 mL	0.8748 mL	1.7497 mL	3.4993 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.