Entecavir Hydrate (BMS200475)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $430 | Check With Us |
| 1g | $645 | Check With Us |
| 5g | $1740 | Check With Us |
: Cat #: V1814 CAS #: 209216-23-9 Purity ≥ 98%
Description: Entecavir hydrate (also known as SQ-34676 and BMS-200475), monohydrated form of entecavir and anti-hepatitis B virus (HBV) agent, is a novel deoxyguanine nucleoside analogue and a reverse transcriptase inhibitor.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 295.29 |
|---|---|
| Molecular Formula | C12H15N5O3.H2O |
| CAS No. | 209216-23-9 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 59 mg/mL (199.8 mM)r |
| Water: 2-3 mg/mLr | |
| Ethanol:<1 mg/mL | |
| Synonyms | Baraclude; BMS-200475; BMS-200475-01; SQ 34676; BMS 200475; BMS 200475-01; SQ34676; BMS200475; SQ-34676; Entecavir monohydrate; . |
| Protocol | In Vivo | Daily oral Entecavir (monohydrate) in doses ranging from 0.02 to 0.5 mg/kg for 1 to 3 months is effective in reducing marmot hepatitis virus (WHV) viraemia levels in chronically infected marmots |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.3865 mL | 16.9325 mL | 33.8650 mL | 67.7300 mL |
| 5mM | 0.6773 mL | 3.3865 mL | 6.7730 mL | 13.5460 mL |
| 10mM | 0.3387 mL | 1.6933 mL | 3.3865 mL | 6.7730 mL |
| 20mM | 0.1693 mL | 0.8466 mL | 1.6933 mL | 3.3865 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.