Ensartinib hydrochloride ( X396)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
100mg	$1125	To Be Confirmed
200mg	$1687	To Be Confirmed
500mg	$2850	To Be Confirmed

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Cat #: V31650 CAS #: 2137030-98-7 Purity ≥ 99%

Description: Ensartinib (formerly known as X-396) is a novel, highly potent, selective, and orally available small molecule inhibitor of ALK (anaplastic lymphoma kinase) with an IC50 less than 4 nM in Ambit assays.

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Molecular Weight (MW)	634.36
Molecular Formula	C26H29Cl4FN6O3
CAS No.	2137030-98-7
SMILES Code	C[C@H](C1=C(Cl)C=CC(F)=C1Cl)OC2=CC(C(NC3=CC=C(C(N4C[C@@H](C)N[C@@H](C)C4)=O)C=C3)=O)=NN=C2N.[H]Cl.[H]Cl
Synonyms	Ensartinib HCl; Ensartinib hydrochloride; Ensartinib dihydrochloride

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	1.5764 mL	7.8820 mL	15.7639 mL	31.5278 mL
5mM	0.3153 mL	1.5764 mL	3.1528 mL	6.3056 mL
10mM	0.1576 mL	0.7882 mL	1.5764 mL	3.1528 mL
20mM	0.0788 mL	0.3941 mL	0.7882 mL	1.5764 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.