Emtricitabine (BW1592)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
1g	$150	Check With Us
10g	$745	Check With Us
20g	$1115	Check With Us

: [email protected] [email protected]

Cat #: V1813 CAS #: 143491-57-0 Purity ≥ 98%

Description: Emtricitabine (BW1592; FTC; Coviracil; Emtriva; Racivir) is a potent nucleoside reverse transcriptase inhibitor (NRTI) with an EC50 of 0.01 µM and has been used for the treatment of both human immunodeficiency virus (HIV) and hepatitis B virus.

References: Saag MS, et al. Emtricitabine, a new antiretroviral agent with activity against HIV and hepatitis B virus. Clin Infect Dis.? 2006 Jan 1;42(1):126-31.

Top Publications Citing Invivochem Products

Product Catalog 2022

Guide to Product Handling

Publications Citing InvivoChem Products

Product Promise

Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	247.25
Molecular Formula	C8H10FN3O3S
CAS No.	143491-57-0
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 49 mg/mL (198.2 mM)r
	Water: 49 mg/mL (198.2 mM)r
	Ethanol: 9 mg/mL (36.4 mM)
Synonyms	BW-1592; BW1592; BW 1592; trade names: Coviracil; Emtriva; Racivir; (-)-FTC; W-201247; W-201248; E1007; 24229-EP2298783A1; 24229-EP2314590A1; AB01275429-01; 3B2-0188

Protocol	In Vitro	Emtricitabine is in vitro active against laboratory strains of HIV-1 and HIV-2, as well as clinical isolates of HIV-1. 50% effective concentration (EC50) ranges from 0.002 to 1.5 μmol/L, depending on the viral isolate and cell line used. Emtricitabine works synergistically with zidovudine and stavudine in vitro, in vitro activity when combined with tashitabine or deshydroxyinosine

These protocols are for reference only. InvivoChem does not independently validate these methods.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	4.0445 mL	20.2224 mL	40.4449 mL	80.8898 mL
5mM	0.8089 mL	4.0445 mL	8.0890 mL	16.1780 mL
10mM	0.4044 mL	2.0222 mL	4.0445 mL	8.0890 mL
20mM	0.2022 mL	1.0111 mL	2.0222 mL	4.0445 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.