EMD638683

This product is for research use only, not for human use. We do not sell to patients.

EMD638683
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$1285Check With Us
250mg$2185Check With Us
500mg$3275Check With Us

Cat #: V9678 CAS #: 1181770-72-8 Purity ≥ 98%

Description: EMD638683 is a potent inhibitor of SGK1 with an IC50 of 3 μM.

References: Ackermann TF, et al. EMD638683, a novel SGK inhibitor with antihypertensive potency. Cell Physiol Biochem. 2011;28(1):137-46.

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Product Promise

Promise
Molecular Weight (MW)364.34
Molecular FormulaC18H18F2N2O4
CAS No.1181770-72-8
SMILES CodeO=C(NNC(C(C1=CC(F)=CC(F)=C1)O)=O)C2=CC=C(O)C(C)=C2CC
SynonymsEMD638683; EMD 638683; EMD-638683
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.7447 mL13.7234 mL27.4469 mL54.8938 mL
5mM0.5489 mL2.7447 mL5.4894 mL10.9788 mL
10mM0.2745 mL1.3723 mL2.7447 mL5.4894 mL
20mM0.1372 mL0.6862 mL1.3723 mL2.7447 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.