EHT-1610
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $2550 | To Be Confirmed |
| 200mg | $3825 | To Be Confirmed |
| 500mg | $6455 | To Be Confirmed |
: Cat #: V20428 CAS #: 1425945-60-3 Purity ≥ 98%
Description: EHT-1610 is a novel, potent and selective DYRK kinase inhibito with IC50s of 0.22, 0.28 nM for DYRK1A and DYRK1B, respectively.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 383.40 |
|---|---|
| Molecular Formula | C18H14FN5O2S |
| CAS No. | 1425945-60-3 |
| Synonyms | EHT-1610; EHT 1610; EHT1610 |
| Protocol | In Vitro | EHT 1610 induces apoptosis of primary ALL cells that were resistant to cytarabine. |
|---|---|---|
| In Vivo | EHT 1610 (20 mg/kg/d; i.p.; twice a day; 3 weeks) shows antileukemia activity against in leukemic aggressive model in mice. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.6082 mL | 13.0412 mL | 26.0824 mL | 52.1648 mL |
| 5mM | 0.5216 mL | 2.6082 mL | 5.2165 mL | 10.4330 mL |
| 10mM | 0.2608 mL | 1.3041 mL | 2.6082 mL | 5.2165 mL |
| 20mM | 0.1304 mL | 0.6521 mL | 1.3041 mL | 2.6082 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.