Efaproxiral Sodium (RSR13)

This product is for research use only, not for human use. We do not sell to patients.

Efaproxiral Sodium (RSR13)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
500mg$250Check With Us
1g$400Check With Us
5g$1010Check With Us

Cat #: V1969 CAS #: 170787-99-2 Purity ≥ 98%

Description: Efaproxiral Sodium (RSR13) is a synthetic allosteric modifier of hemoglobin (Hb) and a bezafibrate analog used for brain metastases originating from breast cancer.

References: Stea B, et al. Efaproxiral red blood cell concentration predicts efficacy in patients with brain metastases. Br J Cancer. 2006 Jun 19;94(12):1777-1784.

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Molecular Weight (MW)363.38
Molecular FormulaC20H23NO4.Na
CAS No.170787-99-2
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 73 mg/mL (200.9 mM)r
Water: 73 mg/mL (200.9 mM)r
Ethanol: 73 mg/mL (200.9 mM)
SMILES CodeCC(C)(OC1=CC=C(CC(NC2=CC(C)=CC(C)=C2)=O)C=C1)C([O-])=O.[Na+]
SynonymsRSR 13 sodium; RSR-13; RSR13
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.7519 mL13.7597 mL27.5194 mL55.0388 mL
5mM0.5504 mL2.7519 mL5.5039 mL11.0078 mL
10mM0.2752 mL1.3760 mL2.7519 mL5.5039 mL
20mM0.1376 mL0.6880 mL1.3760 mL2.7519 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.