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| Size | Price | Stock |
|---|---|---|
| 25mg | $90 | 3-6 Days |
| 50mg | $130 | 3-6 Days |
| 100mg | $190 | 3-6 Days |
| 250mg | $310 | 3-6 Days |
| 500mg | $560 | 3-6 Days |
| 1g | $860 | 3-6 Days |
: Cat #: V0950 CAS #: 1229194-11-9 Purity ≥ 99%
Description: Edoxaban tosylate monohydrate (DU-176b; DU-176; trade name Lixiana), the tosylate salt of edoxaban which is a marketed anticoagulant drug, is a potent, selective, orally bioavailable and direct factor Xa inhibitor with potential anti-coagulant activity. It inhibits Factor Xa with a Ki of 0.561 nM, and exhibits >10 000-fold selectivity over thrombin and FIXa. Edoxaban was developed by Daiichi Sankyo and was approved in July 2011 in Japan for prevention of venous thromboembolisms (VTE) following lower-limb orthopedic surgery. It was also approved by the FDA in January 2015 for the prevention of stroke and non–central-nervous-system systemic embolism.
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| Molecular Weight (MW) | 738.27 |
|---|---|
| Molecular Formula | C24H30ClN7O4S.C7H8O3S.H2O |
| CAS No. | 1229194-11-9 |
| Storage | Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment, avoid exposure to moisture. |
| Synonyms | DU176b; DU 176b; Edoxaban; DU-176; DU 176; DU-176b; DU176; Edoxaban tosylate monohydrate, trade name Lixiana. |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.3545 mL | 6.7726 mL | 13.5452 mL | 27.0904 mL |
| 5mM | 0.2709 mL | 1.3545 mL | 2.7090 mL | 5.4181 mL |
| 10mM | 0.1355 mL | 0.6773 mL | 1.3545 mL | 2.7090 mL |
| 20mM | 0.0677 mL | 0.3386 mL | 0.6773 mL | 1.3545 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.