Ebselen oxide

This product is for research use only, not for human use. We do not sell to patients.

Ebselen oxide
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
50mg$600To Be Confirmed
100mg$1050To Be Confirmed
200mg$1575To Be Confirmed

Cat #: V10990 CAS #: 104473-83-8 Purity ≥ 99%

Description: Ebselen oxide, formed by the oxidation of ebselen, is a novel and potent inhibitor of Histone deacetylase (HDAC1/3/4/5/6/7/8/9).

References: Lieberman OJ, et al. High-throughput screening using the differential radial capillary action of ligand assay identifies ebselen as an inhibitor of diguanylate cyclases. ACS Chem Biol. 2014;9(1):183-192. 

Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products

Product Promise

Promise
Molecular Weight (MW)290.18
Molecular FormulaC13H9NO2Se
CAS No.104473-83-8
ProtocolIn VitroEbselen oxide, is a covalent inhibitor of c-di-GMP allosteric binding to I-site containing proteins, diguanylate cyclase (DGC) activity
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.4461 mL17.2307 mL34.4614 mL68.9227 mL
5mM0.6892 mL3.4461 mL6.8923 mL13.7845 mL
10mM0.3446 mL1.7231 mL3.4461 mL6.8923 mL
20mM0.1723 mL0.8615 mL1.7231 mL3.4461 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.