E64FC26

This product is for research use only, not for human use. We do not sell to patients.

E64FC26
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
1mg$1803-6 Days
5mg$4503-6 Days
10mg$7703-6 Days

Cat #: V37811 CAS #: 2285446-62-8 Purity ≥ 99%

Description: E64FC26 is a potent pan-inhibitor of the protein disulfide isomerase (PDI) family, with IC50s of 1.9, 20.9, 25.9, 16.3 and 25.4 μM for PDIA1, PDIA3, PDIA4, TXNDC5 and PDIA6, respectively. E64FC26 displays antimyeloma activity.

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Molecular Weight (MW)340.37993645668
Molecular FormulaC19H23F3O2
CAS No.2285446-62-8
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

SynonymsE64-FC26; E64 FC26
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.9379 mL14.6895 mL29.3789 mL58.7579 mL
5mM0.5876 mL2.9379 mL5.8758 mL11.7516 mL
10mM0.2938 mL1.4689 mL2.9379 mL5.8758 mL
20mM0.1469 mL0.7345 mL1.4689 mL2.9379 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.