E3 ligase Ligand-Linker Conjugates 14
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $1350 | Check With Us |
| 1g | $2250 | Check With Us |
| 5g | $5695 | Check With Us |
: Cat #: V31992 CAS #: 1957236-21-3 Purity ≥ 99%
Description: E3 ligase Ligand-Linker Conjugates 14 is a synthesized compound that incorporates an E3 ligase ligand and a linker used in PROTAC technology.
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- Physicochemical and Storage Information
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- Related Biological Data
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| Molecular Weight (MW) | 620.53 |
|---|---|
| Molecular Formula | C₂₅H₃₁F₃N₄O₁₁ |
| CAS No. | 1957236-21-3 |
| SMILES Code | O=C(N(C(CCC1=O)C(N1)=O)C2=O)C(C2=CC=C3)=C3OCC(NCCOCCOCCOCCN)=O.FC(F)(F)C(O)= |
| Synonyms | E3 Ligase Ligand-Linker Conjugates 20 TFA |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.6115 mL | 8.0576 mL | 16.1153 mL | 32.2305 mL |
| 5mM | 0.3223 mL | 1.6115 mL | 3.2231 mL | 6.4461 mL |
| 10mM | 0.1612 mL | 0.8058 mL | 1.6115 mL | 3.2231 mL |
| 20mM | 0.0806 mL | 0.4029 mL | 0.8058 mL | 1.6115 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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Volume
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Molecular Weight*
The dilution calculator equation
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Volume(start)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.