Home > Signaling Pathways>New Products>New1>Durlobactam sodium (ETX2514 sodium)
Durlobactam sodium (ETX2514 sodium)

This product is for research use only, not for human use. We do not sell to patients.

Durlobactam sodium (ETX2514 sodium)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
1mg$8003-6 Days
2mg$13003-6 Days
5mg$20003-6 Days
10mg$35003-6 Days
25mg$55003-6 Days
email: [email protected]        [email protected]

Cat #: V20850 CAS #: 1467157-21-6 Purity ≥ 98%

Description: Durlobactam sodium (ETX-2514 sodium, ETX 2514) is a broad-spectrum β-lactamase inhibitor used for the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii. ETX2514 broadly inhibits Ambler class A, C, and D β-lactamases. ETX2514 combined with sulbactam (SUL) in vitro restores sulbactam activity against Acinetobacter baumannii ETX2514-sulbactam (ETX2514SUL) is under development for the treatment of A. baumannii infections. ETX2514 restored β-lactam activity to equal potency against isogenic Pseudomonas aeruginosa strains each overexpressing one of the 10 β-lactamases.

Top Publications Citing Invivochem Products
Product Catalog 2022
Bulletin Board
Guide to Product Handling
Publications Citing InvivoChem Products
Product Promise
Promise
Molecular FormulaC8H10N3NaO6S
CAS No.1467157-21-6
SMILES CodeCC1=C[C@@H](N2OS(=O)(O[Na])=O)CN(C2=O)[C@@H]1C(N)=O           
SynonymsETX2514; ETX-2514; ETX 2514; ETX2514 sodium
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
=
Concentration
 
×
Volume
 
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
×
 
Volume(start)
V1
 
=
 
Concentration(final)
C2
 
×
 
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.