DS-12881479

This product is for research use only, not for human use. We do not sell to patients.

DS-12881479
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
1mg$230To Be Confirmed
5mg$590To Be Confirmed

Cat #: V42199 CAS #: 2373065-59-7 Purity ≥ 99%

Description: DS12881479 is a potent and specific Mnk1 inhibitor (antagonist) with IC50 of 21 nM. DS12881479 may be utilized in cancer-related research.

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Product Promise

Promise
Molecular Weight (MW)301.40656208992
Molecular FormulaC16H19N3OS
CAS No.2373065-59-7
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.3178 mL16.5889 mL33.1778 mL66.3556 mL
5mM0.6636 mL3.3178 mL6.6356 mL13.2711 mL
10mM0.3318 mL1.6589 mL3.3178 mL6.6356 mL
20mM0.1659 mL0.8294 mL1.6589 mL3.3178 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.