Doxorubicin
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
500mg | $250 | Check With Us |
1g | $450 | Check With Us |
5g | $1215 | Check With Us |
Cat #: V2644 CAS #: 23214-92-8 Purity ≥ 98%
Description: Doxorubicin (Adriamycin; NSC-123127; FI-106; Adriblastine; Adrimedac) is a naturally occuring anthracycline antibiotic isolated from the bacterium Streptomyces peucetius var.
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Molecular Weight (MW) | 543.52 |
---|---|
Molecular Formula | C27H29NO11 |
CAS No. | 23214-92-8 |
Storage | -20℃ for 3 years in powder formr |
-80℃ for 2 years in solvent | |
Solubility In Vitro | DMSO: 20 mg/mL (34.48 mM)r |
Water: <1 mg/mLr | |
Ethanol: <1 mg/mL | |
Synonyms | Adriamycin; Hydroxydaunorubicin; ADR; DOX. Code name: FI106; chloridrato de doxorrubicina. Adriamycin; Adriacin; Adriblastina; Adriblastine; Adrimedac; DOXOCELL; Doxolem; Doxorubin; Farmiblastina; Rubex. Abbreviations: ADM; Adria; |
Protocol | In Vitro | Combination of Doxorubicin (Hydroxydaunorubicin) and Simvastatin in the highest tested concentrations (2 μM and 10 μM, respec-tively) kills 97% of the Hela cells |
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These protocols are for reference only. InvivoChem does not
independently validate these methods.
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 1.8399 mL | 9.1993 mL | 18.3986 mL | 36.7972 mL |
5mM | 0.3680 mL | 1.8399 mL | 3.6797 mL | 7.3594 mL |
10mM | 0.1840 mL | 0.9199 mL | 1.8399 mL | 3.6797 mL |
20mM | 0.0920 mL | 0.4600 mL | 0.9199 mL | 1.8399 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.