Diltiazem free base
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 1g | $450 | Check With Us |
| 2g | $750 | Check With Us |
| 5g | $1100 | Check With Us |
: Cat #: V19955 CAS #: 42399-41-7 Purity ≥ 99%
Description: Diltiazem ((Tiazac; CRD-401; Dilticard; RG83606) is a nondihydropyridines (non-DHP) calcium channel blocker with vasodilating activity.
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| Molecular Weight (MW) | 414.52 |
|---|---|
| Molecular Formula | C22H26N2O4S |
| CAS No. | 42399-41-7 |
| SMILES Code | O=C1[C@H](OC(C)=O)[C@H](C2=CC=C(OC)C=C2)SC3=CC=CC=C3N1CCN(C)C |
| Synonyms | CRD 401; Diltiazem; CRD-401; Dilticard; CRD401 |
| Protocol | In Vitro | Diltiazem reduces Ca2+ influx by accelerating inactivation during action potentials, and that the use-dependent blockade is due to increases in the number of channels in a sustained closed state |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.4124 mL | 12.0621 mL | 24.1243 mL | 48.2486 mL |
| 5mM | 0.4825 mL | 2.4124 mL | 4.8249 mL | 9.6497 mL |
| 10mM | 0.2412 mL | 1.2062 mL | 2.4124 mL | 4.8249 mL |
| 20mM | 0.1206 mL | 0.6031 mL | 1.2062 mL | 2.4124 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
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Volume(start)
=
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
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V1
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.