Dihydrotachysterol

This product is for research use only, not for human use. We do not sell to patients.

Dihydrotachysterol
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$550Check With Us
200mg$825Check With Us
500mg$1395Check With Us

Cat #: V15199 CAS #: 67-96-9 Purity ≥ 98%

Description: Dihydrotachysterol is a novel, synthetic vitamin D analogue that is activated in the liver and does not require renal hydroxylation like vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol).

References: I Quack, et al. Dihydrotachysterol therapy for hypoparathyroidism: consequences of inadequate monitoring. Five cases and a review. Exp Clin Endocrinol Diabetes. 2005 Jul;113(7):376-80.

Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products

Product Promise

Promise
Molecular Weight (MW)398.66
Molecular FormulaC28H46O
CAS No.67-96-9
SMILES CodeC[C@H](C(C)C)/C=C/[C@@H](C)[C@H]([C@]1(CCC/2)C)CC[C@@]1([H])C2=CC=C3C[C@@H](O)CC[C@@H]/3C 
SynonymsHytakerol; Parterol; Tachyrol; HSDB 3314; HSDB-3314; HSDB3314; Dihydrotachysterol;
ProtocolIn VitroDihydrotachysterol also increases renal phosphate excretion. Dihydrotachysterol is effective in the elevation of serum calcium by stimulating intestinal calcium absorption and mobilizing bone calcium in the absence of parathyroid hormone and of functioning renal tissue.
In VivoDihydrotachysterol is a potent synthetic vitamin D analogue that is widely available but more expensive than vitamin D2. It has an onset of action and half-life between those of vitamin D2 and calcitriol. Dihydrotachysterol (initially given at 0.03 to 0.08 mg/kg/day for 2 to 3 days. The final dosages range from 0.004 to 0.04 mg/kg/day) is useful for the treatment of hypoparathyroidism.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.5084 mL12.5420 mL25.0840 mL50.1681 mL
5mM0.5017 mL2.5084 mL5.0168 mL10.0336 mL
10mM0.2508 mL1.2542 mL2.5084 mL5.0168 mL
20mM0.1254 mL0.6271 mL1.2542 mL2.5084 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.