Dicoumarol (Dicumarol)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 10g | $250 | Check With Us |
| 50g | $750 | Check With Us |
| 100g | $1125 | Check With Us |
: Cat #: V1911 CAS #: 66-76-2 Purity ≥ 98%
Description: Dicoumarol (also named as Dicumarol) is an oral and competitive inhibitor of NAD(P)H:quinone oxidoreductase 1 (NQO1) and PDK1 with IC50s of 0.37 and 19.42 μM, respectively.
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| Molecular Weight (MW) | 336.29 |
|---|---|
| Molecular Formula | C19H12O6 |
| CAS No. | 66-76-2 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 67 mg/mL (199.2 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: 67 mg/mL (199.2 mM) | |
| SMILES Code | O=C1C(CC2=C(O)C3=CC=CC=C3OC2=O)=C(O)C4=CC=CC=C4O1 |
| Synonyms | NC-034; NSC-17860; NSC-221570; NSC-41834; NC 034; NSC 17860; NSC 221570; NSC 41834; NC034; NSC17860; NSC221570; NSC41834; Dicumarol; Dicumarol; Dicoumarol; Bishydroxycoumarin; Dicoumarin; Melitoxin; Antitrombosin |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.9736 mL | 14.8681 mL | 29.7362 mL | 59.4725 mL |
| 5mM | 0.5947 mL | 2.9736 mL | 5.9472 mL | 11.8945 mL |
| 10mM | 0.2974 mL | 1.4868 mL | 2.9736 mL | 5.9472 mL |
| 20mM | 0.1487 mL | 0.7434 mL | 1.4868 mL | 2.9736 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.