Dehydroaripiprazole (OPC14857; DM14857)

This product is for research use only, not for human use. We do not sell to patients.

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Cat #: V40301 CAS #: 129722-25-4 Purity ≥ 99%

Description: Dehydroaripiprazole (OPC-14857; DM-14857) is a primary active metabolite (formed by dehydrigenation of the quinolone ring) of Aripiprazole, which is an antipsychotic agent and is metabolized by CYP3A4 and CYP2D6 forming mainly Dehydroaripiprazole. Dehydroaripiprazole has with antipsychotic activity equivalent to Aripiprazole.

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Related Biological Data
Stock Solution Preparation
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Molecular Weight (MW)	446.37
Molecular Formula	C₂₃H₂₅Cl₂N₃O₂
CAS No.	129722-25-4
Synonyms	OPC-14857; DM-14857; OPC14857; DM14857; OPC 14857; DM 14857

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.2403 mL	11.2015 mL	22.4029 mL	44.8059 mL
5mM	0.4481 mL	2.2403 mL	4.4806 mL	8.9612 mL
10mM	0.2240 mL	1.1201 mL	2.2403 mL	4.4806 mL
20mM	0.1120 mL	0.5601 mL	1.1201 mL	2.2403 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.