Decamethonium Bromide

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
25g	$220	Check With Us
50g	$380	Check With Us
100g	$570	Check With Us

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Cat #: V1202 CAS #: 541-22-0 Purity ≥ 98%

Description: Decamethonium bromide (Syncurine; Decamethonum; Lopac-D-1260; (DM)Br2 Syncurine), a quaternary ammonium ion, is a short-acting, depolarizing muscle relaxant and/or neuromuscular blocker used in anesthesia to induce paralysis.

References: Br J Anaesth. 2002 May;88(5):692-9.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	418.29
Molecular Formula	C16H38N2.2Br
CAS No.	541-22-0
Storage	-20℃ for 3 years in powder formrr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 34 mg/mL (81.3 mM)rr
	Water: 84 mg/mL (200.8 mM)rr
	Ethanol: 25 mg/mL (59.8 mM)
Solubility In Vivo	Chemical Name: trimethyl-[10-(trimethylazaniumyl)decyl]azanium bromide InChi Key: HLXQFVXURMXRPU-UHFFFAOYSA-L InChi Code: InChI=1S/C16H38N2.2BrH/c1-17(2,3)15-13-11-9-7-8-10-12-14-16-18(4,5)6;;/h7-16H2,1-6H3;2*1H/q+2;;/p-2 SMILES Code: C[N+](CCCCCCCCCC[N+](C)(C)C)(C)C.[Br-].[Br-]
SMILES Code	C[N+](CCCCCCCCCC[N+](C)(C)C)(C)C.[Br-].[Br-]
Synonyms	Syncurine; Decamethonium; Decamethonum; Lopac-D-1260; (DM)Br2

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.3907 mL	11.9534 mL	23.9069 mL	47.8137 mL
5mM	0.4781 mL	2.3907 mL	4.7814 mL	9.5627 mL
10mM	0.2391 mL	1.1953 mL	2.3907 mL	4.7814 mL
20mM	0.1195 mL	0.5977 mL	1.1953 mL	2.3907 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.