DDD107498

This product is for research use only, not for human use. We do not sell to patients.

DDD107498
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1100Check With Us
500mg$1800Check With Us
1g$2700Check With Us

Cat #: V19315 CAS #: 1469439-69-7 Purity ≥ 98%

Description: DDD107498, formerly known as DDD 498, is a multiple-stage antimalarial agent that inhibits protein synthesis.

References: Baragaña B, et al. A novel multiple-stage antimalarial agent that inhibits protein synthesis. Nature. 2015 Jun 18;522(7556):315-20.

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Molecular Weight (MW)462.5694
Molecular FormulaC27H31FN4O2
CAS No.1469439-69-7
SynonymsDDD107498; DDD-107498; DDD 107498; DDD 498; DDD-498; DDD498; MMV121; MMV-121; MMV 121
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.1618 mL10.8092 mL21.6184 mL43.2368 mL
5mM0.4324 mL2.1618 mL4.3237 mL8.6474 mL
10mM0.2162 mL1.0809 mL2.1618 mL4.3237 mL
20mM0.1081 mL0.5405 mL1.0809 mL2.1618 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.