Dasatinib carbaldehyde

This product is for research use only, not for human use. We do not sell to patients.

Dasatinib carbaldehyde
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$2500Check With Us
200mg$3750Check With Us
500mg$6330Check With Us

Cat #: V31695 CAS #: 2112837-79-1 Purity ≥ 99%

Description: Dasatinib carbaldehyde, an analog of Dasatinib (BMS-354825; Sprycel) which is an approved anticancer drug, binds to IAP ligand via a linker to form SNIPER .

References: Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108(8):1657-1666.

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Molecular Weight (MW)471.96
Molecular FormulaC21H22ClN7O2S
CAS No.2112837-79-1
SynonymsBMS-354825 carbaldehyde
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.1188 mL10.5941 mL21.1882 mL42.3765 mL
5mM0.4238 mL2.1188 mL4.2376 mL8.4753 mL
10mM0.2119 mL1.0594 mL2.1188 mL4.2376 mL
20mM0.1059 mL0.5297 mL1.0594 mL2.1188 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.