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| Size | Price | Stock |
|---|---|---|
| 250mg | $400 | Check With Us |
| 500mg | $550 | Check With Us |
| 1g | $825 | Check With Us |
: Cat #: V19109 CAS #: 1042385-75-0 Purity ≥ 98%
Description: Dacomitinib (aslo known as PF299804, PF299; trade name: Vizimpro) is a novel, potent, orally bioavailable, highly selective, irreversible, second generation pan-ErbB inhibitor, mostly to EGFR with with IC50 of 6 nM, 45.7 nM and 73.7 nM for EGFR, ERBB2, and ERBB4, respectively in cell-free assays.
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| Molecular Weight (MW) | 487.96 |
|---|---|
| Molecular Formula | C24H27ClFN5O3 |
| CAS No. | 1042385-75-0 |
| SMILES Code | O=C(NC1=CC2=C(NC3=CC=C(F)C(Cl)=C3)N=CN=C2C=C1OC)/C=C/CN4CCCCC4.[H]O[H] |
| Synonyms | PF 299804; PF-299; PF299; PF 299; PF-00299804-03; Vizimpro; PF-00299804; PF00299804; PF 00299804; PF299804; PF-299804; |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.0493 mL | 10.2467 mL | 20.4935 mL | 40.9870 mL |
| 5mM | 0.4099 mL | 2.0493 mL | 4.0987 mL | 8.1974 mL |
| 10mM | 0.2049 mL | 1.0247 mL | 2.0493 mL | 4.0987 mL |
| 20mM | 0.1025 mL | 0.5123 mL | 1.0247 mL | 2.0493 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.