Daclatasvir dihydrochloride

This product is for research use only, not for human use. We do not sell to patients.

Daclatasvir dihydrochloride
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$100In Stock
500mg$160In Stock
1g$270In Stock
2g$450In Stock
email: sales@invivochem.com        sales@invivochem.cn

Cat #: V3156 CAS #: 1009119-65-6 Purity ≥ 99%

Description: Daclatasvir dihydrochloride (BMS790052; EBP883; BMS-790052; EBP-883; Daklinza ), the dihydrochloride salt of Daclatasvir, is a novel, highly potent and selective HCV NS5A protease inhibitor that has been approved in 2014 in EU for use in combination with sofosbuvir for the treatment of hepatitis C (HCV) by causing a decrease in serum HCV RNA levels. With an EC50 of 9–50 pM, it inhibits the HCV NS5A protease.

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Molecular Weight (MW)738.88
Molecular FormulaC40H52N8Cl2O6
CAS No.1009119-65-6
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

Note: Please store this product in a sealed and protected environment, avoid exposure to moisture.

SynonymsBMS-790052; BMS 790052; EBP 883;EBP-883; EBP883; BMS790052; Daclatasvir 2HCl; Daclatasvir HCl; EBP-883; Daclatasvir 2HCl; Daklinza; Daclatasvir (dihydrochloride); Daclatasvir dihydrochloride; Daklinza (trade name)
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.3534 mL6.7670 mL13.5340 mL27.0680 mL
5mM0.2707 mL1.3534 mL2.7068 mL5.4136 mL
10mM0.1353 mL0.6767 mL1.3534 mL2.7068 mL
20mM0.0677 mL0.3383 mL0.6767 mL1.3534 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.