Cyproterone Acetate

This product is for research use only, not for human use. We do not sell to patients.

Cyproterone Acetate
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5g$650Check With Us
10g$1100Check With Us
20g$1650Check With Us

Cat #: V1768 CAS #: 427-51-0 Purity ≥ 98%

Description: Cyproterone acetate (Cyprone, Androcur, Cyprostat,Cyprohexal, Ciproterona, Cyproteron, Procur, Cyproteronum, Neoproxil, Siterone), an analog of 17-hydroxyprogesterone, is an androgen receptor (AR) antagonist with potential antitumor activity.

References: Migally N. Effect of cyproterone acetate on the structure of the adrenal cortex. Arch Androl. 1979;2(2):109-115.

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Molecular Weight (MW)416.94
Molecular FormulaC24H29ClO4
CAS No.427-51-0
Storage-20℃ for 3 years in powder formrr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 83 mg/mL (199.1 mM)rr
Water: <1 mg/mLrr
Ethanol: 10 mg/mL (24.0 mM)
Solubility In Vivo1% DMSO+30% polyethylene glycol+1% Tween 80: 20 mg/mL
ProtocolIn VivoAdult male C57 BL/6J mice injected with 0.08 mg/g of cyproterone acetate showed an increase in cellular lipid content in the zona fasciculata and zona retjculans of the adrenal cortex
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.3984 mL11.9921 mL23.9843 mL47.9685 mL
5mM0.4797 mL2.3984 mL4.7969 mL9.5937 mL
10mM0.2398 mL1.1992 mL2.3984 mL4.7969 mL
20mM0.1199 mL0.5996 mL1.1992 mL2.3984 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.